class="Serp__item__snippet--34vQF">Yes, you can take Benadryl (Diphenhydramine) and Sertraline (Zoloft) together. Benadryl is an antihistamine and Sertraline is an antidepressant. Of note, sometimes antidepressants can make you tired, especially if you are just getting used to them. canadianpillsbuy.com buy cialis without presc